Permeability of gentamicin into the inside of Bacillus subtilis spores |
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Authors: | Kunio Tochikubo Satoshi Kozuka Yoko Yasuda |
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Institution: | Department of Microbiology, Nagoya City University Medical School, Nagoya, Japan |
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Abstract: | Abstract The penetration of gentamicin into the inside of Bacillus subtilis spores was examined by an immunoelectron microscopy method with colloidal gold-immunoglobulin G complex. The colloidal gold particles were located mainly in the coat regions of spores and were not observed in the cortex or core regions. This result suggests the existence of an outer membrane inside the coat region as the primary permeability barrier to gentamicin. |
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Keywords: | Bacillus subtilis Spore Spore coat Gentamicin |
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