The allogeneic response and tumor immunity |
| |
Authors: | Fabre J W |
| |
Institution: | Department of Clinical Sciences, Institute of Liver Studies Guy's, King's and St Thomas' School of Medicine, London, UK. john.fabre@kcl.ac.uk |
| |
Abstract: | The strong allogeneic response to donor MHC molecules in transplantation and the weak response to tumor antigens represent two important and divergent but potentially interactive immune responses. A patient's response to allogeneic MHC molecules might promote an effective T-cell response to self MHC-restricted tumor peptides and the possibilities for this are discussed here. These allogeneic responses might successfully be harnessed to promote the immune eradication of metastatic cancer. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|