Cultivation of Hansenula polymorpha in tower loop reactors |
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Authors: | H Buchholz R Luttmann W Zakrzewski K Schügerl |
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Institution: | 1. Institut für Technische Chemie der Universit?t Hannover, Callinstra?e 3, D-3000, Hannover, Germany 2. Institut für Regelungstechnik der Univesit?t Hannover, Callinstra?e 3, D-3000, Hannover, Germany
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Abstract: | Summary Hansenula polymorpha was cultured for extended periods in an air lift tower loop reactor (15 cm in diameter with a 275 cm
bubbling layer height) with ethanol and/or glucose as the substrates. At constant operation conditions variations of the following
parameters were measured: the consumption of the substrate and oxygen, the production of CO2 and biomass, the longitudinal concentration profile of dissolved oxygen, the oxygen and substrate yield coefficients, the
respiratory quotient and the specific interfacial area and volumetric mass transfer coefficient. The influence of the microorganisms
on the oxygen transfer rate is discussed especially in the case of glucose repression. |
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