Effects of Transport Stress on Serum Alkaline Phosphatase Activity in Beagle
Dogs |
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Authors: | Takehiro Ochi Ippei Nishiura Mitsuyoshi Tatsumi Yoshimi Hirano Kouichi Yahagi Yasuhiro Sakurai Yuji Sudo Hironari Koyama Yuichi Hagita Yoshikatsu Fujimoto Shinji Kitamura Hideki Hashimoto Tomoya Nakamura Asobi Yamada Masayoshi Tanimoto Noriko Nishina |
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Institution: | 1)Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1–6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan;2)KAC Co., Ltd., 1–6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan;3)Drug Safety Research Labs, Astellas Pharma Inc., 1–6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan |
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Abstract: | Here, to determine the effects of transport stress on blood parameters in dogs, we
investigated the changes in hematologic and serum chemical parameters in healthy beagle
dogs transported from Beijing, China, to Osaka, Japan, to obtain the background data. Only
the activity of serum alkaline phosphatase increased clearly upon arrival, a change
attributed to transport stress, but the activity gradually reduced afterward. No marked
changes in levels of other blood parameters were noted. Our findings here suggest that
alkaline phosphatase is a useful tool for studying transport stress. |
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Keywords: | alkaline phosphatase blood parameter dog transport stress |
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