Correlation between nucleotide composition and folding energy of coding sequences with special attention to wobble bases |
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| Authors: | Jan C Biro |
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| Affiliation: | (1) Homulus Foundation, 612 S Flower Str., #1220, 90017 Los Angeles, CA, USA |
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| Abstract: | Background The secondary structure and complexity of mRNA influences its accessibility to regulatory molecules (proteins, micro-RNAs), its stability and its level of expression. The mobile elements of the RNA sequence, the wobble bases, are expected to regulate the formation of structures encompassing coding sequences. |
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