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Determination of the free radical scavenging activity of dihydropyran-2,4-diones
Authors:de Souza Laura Cristiane  de Araújo Stella Maris Soares  de Oliveira Imbroisi Dennis
Institution:LaSO, Laboratório de Síntese Organica, Departamento de Química, CCEN, Universidade Federal de Alagoas, 57.072-970 Maceió, AL, Brazil.
Abstract:The antioxidant activities of four synthetic dihydropyran-2,4-diones have been established through the determination of their abilities to inhibit free radicals using DPPH(*) as the stable radical. Whilst all of the compounds exhibited high inhibition percentages, the most active member of the group was 6-phenyl-dihydropyran-2,4-dione. The antioxidant activity of the dihydropyran-2,4-diones is reported here for the first time and extends our knowledge of the range of valuable biological activities associated with this group of compounds.
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