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Alkaloids and coumarins of Skimmia reevesiana
Institution:1. Department of Pharmacy, University “G. D''Annunzio” of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti Scalo (CH), Italy;2. Department of Agrobioscience, Kobe University, 1-1 Rokkodai-cho, Nada-ku, 6578501 Kobe, Japan
Abstract:Two new quinolone alkaloids, reevesianine-A and -B, along with five known furoquinoline alkaloids, 7-isopentenyloxy-γ-fagarine, skimmianine, haplopine, evodine, evoxine, and nine known coumarins, 7-isopentenyloxy-8-isopentenylcoumarin, auraptene, osthol, isomeranzin, pranferin, R-(?)-columbianetin, umbelliferone, meranzin hydrate and skimmin, were isolated from the root and stem bark of Skimmia reevesiana collected in Taiwan. The structures of reevesianine-A and -B were established by chemical and spectroscopic methods.
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