Entada saponin-III,a saponin isolated from the bark of Entada phaseoloides |
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| Institution: | 1. National Cancer Center Research Institute, Tsukiji 5-1-1, Chuo-ku, 104 Tokyo, Japan;2. Ateneo de Manila University, P.O. Box No. 154, Manila, Philippines;3. Jeol Ltd, 1418 Nakagami, Akishima, 196 Tokyo, Japan;1. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, 210009, China;2. Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 211198, China;3. Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing 210009, China;1. 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Greece;2. 2nd Department of Critical Care Medicine, National and Kapodistrian University of Athens, Medical School, Greece;3. 1st Department of Critical Care Medicine, National and Kapodistrian University of Athens, Medical School, Greece;4. Intensive Care Unit, “Korgialeneion-Benakeion” General Hospital, Athens, Greece;5. 1st Department of Orthopaedics, National and Kapodistrian University of Athens, Medical School, Greece;6. Department of Internal Medicine, Radboud University Nijmegen, The Netherlands;1. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China;2. Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China;3. Jiangxi Qingfeng Pharmaceutical Corporation, Ganzhou 341000, China;4. Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, China;5. Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 211198, China;1. The Department of Pain Clinic of the First Affiliated Hospital, Harbin Medical University, Harbin, 150001, PR China;2. The Department of Tumor of the Second Affiliated Hospital, Harbin Medical University, Harbin, 150086, PR China;3. The Department of Abdominal Ultrasonography Room of the First Affiliated Hospital, Harbin Medical University, Harbin, 150001, PR China;4. The Anesthesiology Department of the Tumor Hospital Affiliated to Harbin Medical University, Harbin, 150081, PR China;1. School of Life Science, Beijing Institute of Technology, Beijing 100081, PR China;2. Beijing BIT&GY Pharmaceutical R&D Co. Ltd., Beijing 100081, PR China;1. Department of Plant Anatomy, Institute of Biology, Eötvös Loránd University, Pázmány Péter sétány 1/C, Budapest 1117, Hungary;2. Department of Pharmaceutical Chemistry, Semmelweis University, H?gyes Endre utca 7, Budapest 1092, Hungary;3. Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Gellért tér 4, Budapest 1111, Hungary;4. Department of Analytical Chemistry, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, Budapest 1117, Hungary;5. Department of Pharmacognosy, Semmelweis University, Üll?i út 26, Budapest 1085, Hungary |
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| Abstract: | The structure of Entada saponin (ES)-III, one of the main saponins of Entada phaseoloides bark, was established to be 3-O-β-d-xylopyranosyl (1 → 2)-α-l-arabinopyranosyl (1 → 6)] β-l-glucopyranosyl (1 → 4)]-2-acetamido-2-deoxy-β-l-glucopyranosyl-28-O-β-l-apiofuranosyl (1 → 3)-β-d-xylopyranosyl (1 → 2)] (2-O-acetoxyl)-β-d-glucopyranosyl-(1 → 4)] (6 ? O(R) (?)2,6-dimethyl-2-trans-2,7-octadienoyl)-β-d-glucopyranosyl echinocystic acid. |
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