Entadamide B,a second new sulphur-containing amide from Entada phaseoloides |
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| Affiliation: | 1. Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142, Japan;2. Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10500, Thailand;1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China;2. School of Pharmacy, Shandong Wanjie Medical Institute, Zibo 255213, China;3. Department of Traditional Chinese Medicine, Shanghai Municipal Xuhui District Central Hospital, Shanghai 201620, China;4. Ministry of Education Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China;1. National Institute for Public Health and the Environment (RIVM), PO Box 1, NL-3720BA Bilthoven, The Netherlands;2. Department of Toxicogenomics, Maastricht University, PO Box 616, NL-6200 MD Maastricht, The Netherlands;3. Toxicology and Risk Assessment, TNO Triskelion, PO Box 844, NL-3700 AV Zeist, The Netherlands;1. Department of Pathophysiology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Slovakia;2. Biomedical Center Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Slovakia |
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| Abstract: | A second new sulphur-containing amide, entadamide B, has been isolated from the dry seeds of Entada phaseoloides Merr. together with entadamide A. Entadamide B was characterized by spectroscopic methods as N-(2-hydroxyethyl)-3,3-bis(methylthi and was synthesized in two steps from propiolic acid. |
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