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Bis-benzylisoquinoline alkaloids from Abuta pahni
Institution:1. O.R.S.T.O.M.-I.B.B.A., CP 824, La Paz, Bolivia;2. C.C.I.P.E., BP 5055, 34033 Montpellier Cedex, France;1. Vascular Biology Lab, AU-KBC Research Centre, Anna University, Chennai 600044, India;2. Department of Biotechnology, Anna University, Chennai 600044, India;3. Stem Cell and Cancer Biology Laboratory, School of Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia;1. A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1 Favorsky Str., 664033, Irkutsk, Russian Federation;2. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 Lavrentiev Ave., 630090, Novosibirsk, Russian Federation;3. Novosibirsk State University, 2 Pirogova Str., Novosibirsk, 630090, Russian Federation;1. Key Laboratory of Preparation and Applications of Environmentally Friendly Materials (Jilin Normal University), Ministry of Education China, Siping 136000, China;2. College of Chemistry, Jilin Normal University, Siping 136000, China;3. College of Chemistry, Baicheng Normal University, Baicheng, 130032, China;4. Siping Institute for Food and Drug Control, Siping 136000, China;1. Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Republic of Korea;2. School of Materials Science & Engineering, Engineering Research Institute (ERI), Gyeongsang National University, Jinju 660-701, Republic of Korea;3. Department of Chemistry, Engineering Research Institute (ERI), Gyeongsang National University, Jinju 660-701, Republic of Korea
Abstract:From the stems of Abuta pahni, eight isoquinoline alkaloids were isolated and identified by spectroscopic methods and chemical correlations. Three of the bis-benzylisoquinoline alkaloids are new and were assigned the structures 2′-N-nordaurisoline, 2-N-methyllindoldhamine and 2′-N-methyllindoldhamine. The other known alkaloids were coclaurine, daurisoline, lindoldhamine, dimethyllindoldhamine, stepharine and thalifoline.
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