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Triterpenes from Maytenus horrida
Affiliation:1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, People''s Republic of China;2. Department of Cell and Molecular Biology, Research Institute of Orthopedics & Traumatology, Foshan Hospital of TCM, Foshan 528000, People''s Republic of China;1. State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, PR China;2. Department of Chemistry, University of Pennsylvania, 231 S. 34 Street, Philadelphia, PA 19104-6323, United States;1. Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Wuhan 430062, China;2. Hubei Key Laboratory of Bio-Technology of Traditional Chinese Medicine, Hubei University, Wuhan 430062, China;3. Shenzhen Institute of Geriatrics, Shenzhen 518020, China
Abstract:The new triterpene 1β,3β,11α-trihydroxyolean-12-ene and the already known compounds, lupeol, germanicol, 3β-hydroxy-glutin-5-ene, β-amyrin, 3β-hydroxyolean-9(11),12-diene, 3-oxo-olean-9(11),12-diene, 3β,11α-dihydroxyolean-18-ene,3β,11α-dihydroxyolean-12-ene, 3β,29-dihydroxy-glutin-5-ene and dulcitol, were isolated from the root bark of Maytenus horrida.
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