Identification of two human ferritin H genes on the short arm of chromosome 6 |
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| Authors: | I J Dugast P Papadopoulos E Zappone C Jones K Theriault G J Handelman R Benarous J W Drysdale |
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| Affiliation: | Department of Biochemistry, Tufts University, Boston, Massachusetts 02111. |
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| Abstract: | We have found by analyses of human-hamster hybrid cells that two human ferritin H genes lie near the locus of the iron storage disease idiopathic hemochromatosis on chromosome 6p. One of these genes was isolated and shown to be a processed pseudogene. Comparison of its sequence with those of other ferritin H pseudogenes indicates that they may be derived from a functional H gene other than that on chromosome 11. |
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