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An abnormality of oestrogen feedback in amenorrhoea-galactorrhoea. |
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| Authors: | M R Glass R W Shaw W R Butt R L Edwards D R London |
| Abstract: | Fourteen patients with amenorrhoea and hyperprolactin-anemia but no evidence of pituitary tumours were each given an intramuscular injection of 1 mg oestradiol benzoate. Thirteen patients failed to release luteinizing hormone in response to the oestrogen. This hypothalamic abnormality may help to explain the menstrual disturbances in subjects with hyperprolactinaemia. |
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