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Optimization of fermentation conditions for thermostable cellulase production byThielavia terrestris
Authors:Argyrios Margaritis  Rosemina F Merchant
Institution:(1) Department of Chemical and Biochemical Engineering, University of Western Ontario, N6A 5B9 London, Ontario, Canada;(2) Present address: Vaccine Research and Production, Vetrepharm Inc., Putnam, Ontario, Canada
Abstract:Summary Of the eighteen different carbon sources, solka floc was optimal for the induction of cellulases by the thermophilic fungusThielavia terrestris. The temperature optimum for growth was between 44–52°C. The effect of initial and controlled pH on fungal growth and cellulase production was investigated and the results obtained showed that the maximum volumetric productivity (6.07 I.U./1 per h) of filter paper activity was achieved when the pH was controlled at 4.5–5.0.
Keywords:Optimization  Cellulase  Thermostable enzymes  Cellulolytic fungi  Thielavia  Fermentation  Production
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