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多囊卵巢综合征并发抑郁症的研究现状
引用本文:郝淑贤,于秋晓,宋茜,沈奇杨,范丽婷,祝世功,康继宏. 多囊卵巢综合征并发抑郁症的研究现状[J]. 生理科学进展, 2017, 0(4): 257-263
作者姓名:郝淑贤  于秋晓  宋茜  沈奇杨  范丽婷  祝世功  康继宏
作者单位:北京大学医学部生理学与病理生理学系,北京,100191
基金项目:973计划(2013CB945202),国家自然科学基金(81670733;81100398)资助课题
摘    要:多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄女性最常见的内分泌疾病之一,表现为生殖和代谢异常。近些年来,越来越多的人群学研究发现,PCOS病人患精神心理疾病,尤其是抑郁症的发生率高于正常人群。本文概述了PCOS并发抑郁症的相关危险因素和可能机制,并简要论述了PCOS的治疗药物对抑郁症作用的最新研究进展。

关 键 词:多囊卵巢综合征  抑郁症  单胺神经递质

The Current Research on Polycystic Ovary Syndrome Complicated by Depression
HAO Shu-Xian,YU Qiu-Xiao,SONG Xi,SHEN Qi-Yang,FAN Li-Ting,ZHU Shi-Gong,KANG Ji-Hong. The Current Research on Polycystic Ovary Syndrome Complicated by Depression[J]. Progress in Physiological Sciences, 2017, 0(4): 257-263
Authors:HAO Shu-Xian  YU Qiu-Xiao  SONG Xi  SHEN Qi-Yang  FAN Li-Ting  ZHU Shi-Gong  KANG Ji-Hong
Abstract:Polycystic ovary syndrome (PCOS), mainly characterized by metabolic disturbances and reproductive comorbidities, is one of the most common endocrine disorders among women of reproductive age.Recently, increasing population studies have reported that the prevalence of psychological disorders, particularly depression, in women with PCOS is significantly higher than in healthy controls.In this review, we summarize the possible risk factors in women with PCOS complicated by depression and the underlying mechanisms involved in.Moreover, the effects of the current medications for the treatment of PCOS on depression are also discussed.
Keywords:polycystic ovary syndrome  depression  monoamine neurotransmitters
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