Species of Borrelia distinguished by restriction site polymorphisms in 16S rRNA genes |
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| Authors: | David Ralph Daniele Postic Guy Baranton Charles Pretzman Michael McClelland |
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| Affiliation: | Unitéde Bacteriologie Moleculaire et Médicale, Institut Pasteur, Paris, France; California Institute of Biological Research, La Jolla, California, USA |
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| Abstract: | Abstract Three phyletic groups of Borrelia associated with Lyme disease, B. burgdorferi, B. garinii and group VS461 can be distinguished from each other and other species of Borrelia by Bfa I restriction site polymorphisms in PCR amplified 16S rRNA genes. One strain isolated from an Ixodes pacificus tick in California that was previously unclassifiable was distinguishable from B. burgdorferi by an Mnl I restriction site polymorphism. |
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| Keywords: | Polymerase chain reaction Restriction site polymorphism Ribosomal RNA gene Borrelia Lyme disease |
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