The tricarboxylic acid cycle in <Emphasis Type="Italic">Shewanella oneidensis</Emphasis> is independent of Fur and RyhB control |
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| Authors: | Yunfeng Yang Lee Ann McCue Andrea B Parsons Sheng Feng Jizhong Zhou |
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| Institution: | 1.Department of Environmental Science and Engineering,Tsinghua University,Beijing,China;2.Biosciences Division,Oak Ridge National Laboratory,Oak Ridge,USA;3.Pacific Northwest National Laboratory,Richland,USA;4.Department of Biostatistics and Bioinformatics,Duke University,Durham,USA;5.Institute for Environmental Genomics and Department of Botany and Microbiology,University of Oklahoma,Norman,USA |
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| Abstract: | Background It is well established in E. coli and Vibrio cholerae that strains harboring mutations in the ferric uptake regulator gene (fur) are unable to utilize tricarboxylic acid (TCA) compounds, due to the down-regulation of key TCA cycle enzymes, such as AcnA
and SdhABCD. This down-regulation is mediated by a Fur-regulated small regulatory RNA named RyhB. It is unclear in the γ-proteobacterium
S. oneidensis whether TCA is also regulated by Fur and RyhB. |
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