| 阳离子脂质体的转染机制及转染效率影响因素 |
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| 引用本文： | 陈彦祥,乔卫红,刘栋良,李宗石. 阳离子脂质体的转染机制及转染效率影响因素[J]. 生物工程学报, 2007, 23(5): 776-780 |
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| 作者姓名： | 陈彦祥 乔卫红 刘栋良 李宗石 |
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| 作者单位： | 1. 大连理工大学精细化工国家重点实验室,大连,116012
2. 东华大学化学与化工学院,上海,201620 |
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| 摘 要： | 阳离子脂质体是一种非常具有发展前景的基因载体。简要介绍了阳离子脂质体的结构特点;着重讨论了阳离子脂质体作为基因载体时介导基因转移的机制以及在转染过程中对基因转染效率产生影响的主要因素。
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| 关 键 词： | 阳离子脂质体 基因治疗 转染机制 转染效率 |
| 文章编号： | 1000-3061（2007）05-0776-05 |
| 修稿时间： | 2007-01-05 |
The Mechanism and Efficiency Affecting Factor of Cationic Liposome Transfection |
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| CHEN Yan-Xiang,QIAO Wei-Hong,LIU Dong-Liang and LI Zong-Shi. The Mechanism and Efficiency Affecting Factor of Cationic Liposome Transfection[J]. Chinese journal of biotechnology, 2007, 23(5): 776-780 |
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| Authors: | CHEN Yan-Xiang QIAO Wei-Hong LIU Dong-Liang LI Zong-Shi |
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| Affiliation: | 1 State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian 116012,China2 College of Chemistry and Chemical Engineering,Donghua University,Shanghai 201620,China |
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| Abstract: | Cationic liposome is a greatly promising gene carrier.In this paper,the structure trait of cationic liposome was briefly introduced,the mechanism of cationic liposomes mediated gene delivery and the main influencing factor of transfection efficiency in the transfection process were discussed chiefly. |
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| Keywords: | cationic liposome gene therapy transfection mechanism transfection efficiency |
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