To die or not to die: Shigella has an answer |
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| Authors: | Rudel Thomas |
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| Affiliation: | Biocenter, Department of Microbiology, University of Würzburg, Würzburg, Germany. thomas.rudel@biozentrum.uni-wuerzburg.de |
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| Abstract: | Invasion of epithelial cells by Shigella is a critical step in the pathogenesis of bacillary dysentery. In this issue of Cell Host & Microbe, Bergounioux et?al. (2012) uncover a complex interplay of proinvasion, prosurvival, and prodeath signals centered on the activation of calpain protease by the Shigella VirA protein. |
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