Cofactors required for TLR7- and TLR9-dependent innate immune responses期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Cofactors required for TLR7- and TLR9-dependent innate immune responses

Authors:	Chiang Chih-Yuan Engel Alex Opaluch Amanda M Ramos Irene Maestre Ana M Secundino Ismael De Jesus Paul D Nguyen Quy T Welch Genevieve Bonamy Ghislain M C Miraglia Loren J Orth Anthony P Nizet Victor Fernandez-Sesma Ana Zhou Yingyao Barton Gregory M Chanda Sumit K

Affiliation:	Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

Abstract:	Download : Download high-res image (492KB) Download : Download full-size image Highlights? RNAi and systems-based analysis identified 190 TLR7/9 signaling cofactors ? Pathway crossprofiling enabled mapping cofactors to specific NFκB signaling modules ? HRS is a mediator of ubiquitin-dependent nondegradative endosomal TLR sorting

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