Decreased cupric ion uptake as the mechanism for cupric ion resistance in Escherichia coli |
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| Authors: | CM Cotter JT Trevors GM Gadd |
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| Institution: | Department of Environmental Biology, University of Guelph, Guelph, Ont. N1G 2W1, Canada;Department of Biological Sciences, University of Dundee, Dundee DD1 4HN, U.K. |
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| Abstract: | Abstract Plasmid-encoded copper (Cu2+) resistance in Escherichia coli was due to decreased uptake of Cu2+. The Cu2+-resistant E. coli Rtsl strain contained a 60 MDa plasmid which is known to encode for both Cu2+ and kanamycin resistance. A plasmid-free derivative of the same organism exhibited a greater uptake of Cu2+, and sensitivity to Cu2+ in both respiration and growth studies than the E. coli Rtsl strain. |
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| Keywords: | Cu2+ resistance Escherichia coli Plasmid |
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