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GS2PATH: a web-based integrated analysis tool for finding functional relationships using gene ontology and biochemical pathway data
Authors:Yang Jin Ok  Charny Park  Lee Byungwook  Kim Sangsoo  Bhak Jong  Woo Hyun Goo
Institution:Korean BioInformation Center, KRIBB, Daejeon 305-806, Korea.
Abstract:GS2PATH is a Web-based pipeline tool to permit functional enrichment of a given gene set from prior knowledge databases, including gene ontology (GO) database and biological pathway databases. The tool also provides an estimation of gene set enrichment, in GO terms, from the databases of the KEGG and BioCarta pathways, which may allow users to compute and compare functional over-representations. This is especially useful in the perspective of biological pathways such as metabolic, signal transduction, genetic information processing, environmental information processing, cellular process, disease, and drug development. It provides relevant images of biochemical pathways with highlighting of the gene set by customized colors, which can directly assist in the visualization of functional alteration.

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Keywords:gene set enrichment test  gene ontology  pathways  integrated search
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