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A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease
Authors:Bruce P Ayati  Claire M Edwards  Glenn F Webb  John P Wikswo
Affiliation:(1) Department of Mathematics, University of Iowa, Iowa City, IA, 52242, USA;(2) Vanderbilt Center for Bone Biology, Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA;(3) Department of Mathematics, Vanderbilt University, Nashville, TN, 37235, USA;(4) Departments of Biomedical Engineering, Molecular Physiology and Biophysics, and Physics and Astronomy, Vanderbilt University, Nashville, TN, 37235, USA;(5) Vanderbilt Institute for Integrative Biosystems Research and Education, 6809 Stevenson Center, VU Station B, 351807, Nashville, 37235-180, TN
Abstract:

Background  

Multiple myeloma is a hematologic malignancy associated with the development of a destructive osteolytic bone disease.
Keywords:
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