Genetic variation in Staphylococcus aureus surface and immune evasion genes is lineage associated: implications for vaccine design and host-pathogen interactions |
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Authors: | Alex J McCarthy Jodi A Lindsay |
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Affiliation: | (1) Centre for Infection, Department of Cellular and Molecular Medicine, St George's, University of London, Cranmer Terrace, SW17 0RE London, UK |
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Abstract: | Background S. aureus is a coloniser and pathogen of humans and mammals. Whole genome sequences of 58 strains of S. aureus in the public domain and data from multi-strain microarrays were compared to assess variation in the sequence of proteins known or putatively interacting with host. |
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