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Functional Analysis: Evaluation of Response Intensities - Tailoring ANOVA for Lists of Expression Subsets
Authors:Fabrice Berger  Bertrand De Meulder  Anthoula Gaigneaux  Sophie Depiereux  Eric Bareke  Michael Pierre  Benoît De Hertogh  Mauro Delorenzi  Eric Depiereux
Institution:1.Bioinformatics and Biostatistics Laboratory,Molecular Biology Research Unit (URBM), FUNDP University of Namur,Namur,Belgium;2.Swiss Institute of Bioinformatics,Lausanne,Switzerland
Abstract:

Background  

Microarray data is frequently used to characterize the expression profile of a whole genome and to compare the characteristics of that genome under several conditions. Geneset analysis methods have been described previously to analyze the expression values of several genes related by known biological criteria (metabolic pathway, pathology signature, co-regulation by a common factor, etc.) at the same time and the cost of these methods allows for the use of more values to help discover the underlying biological mechanisms.
Keywords:
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