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Isolation and transportation ofTreponema pertenue in golden hamsters
Authors:Sally L Liska  Peter L Perine  Elizabeth F Hunter  John A Crawford  John C Feeley
Institution:(1) Imperial County Health Department, 92243 El Centro, California, USA;(2) Department of Epidemiology, School of Public Health, University of Washington, 98195 Seattle, Washington, USA;(3) Bacteriology Division, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, 30333 Atlanta, Georgia, USA
Abstract:Ten golden hamsters of the CB/Ss LAK strain were flown to Africa, and six of them were inoculated with lesion exudate from yaws patients in an attempt to isolate newer strains ofTreponema pertenue. Three of the six hamsters developed yaws lesions from which treponemes were isolated. Two isolates have been successfully maintained in laboratory animals; these have been designated CDC isolates numbers 1 and 2. Since older stock strains may be altered through repeated animal passage, these fresh isolates will be useful in antigenic and immunological analyses of the pathogenic treponemes. This strain of golden hamster is susceptible to yaws infection, easy to care for, and shipped safely by air; therefore, they are a practical means of transportingT. pertenue.
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