Design, synthesis, and anti-Helicobacter pylori activity of erythromycin A (E)-9-oxime ether derivatives |
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| Authors: | Nam Ghilsoo Kang Tae Won Shin Jung Hyu Choi Kyung Il |
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| Affiliation: | Biochemicals Research Center, Korea Institute of Science and Technology, PO Box 131, Cheongryang, Seoul, Republic of Korea. |
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| Abstract: | The synthesis and anti-Helicobacter pylori (H. pylori) activity evaluation of a new series of erythromycin A (E)-9-oxime ether derivatives are described. These compounds exhibited comparable in vitro anti-H. pylori activity and improved acid stability compared to the reference compound clarithromycin. |
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