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Effect of constituting amino acid residue numbers on molecularly imprinted chiral recognition sites
Authors:Kondo Yoshiko  Morita Yukihiro  Fujimoto Atushi  Tounai Masahiko  Kimura Satoshi  Yoshikawa Masakazu
Affiliation:Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan.
Abstract:In the present study, the effect of constituting amino acid residue numbers of oligopeptide derivatives, which are candidate materials to construct molecular recognition sites, on chiral recognition ability was investigated. Chiral recognition sites were formed from oligopeptide derivatives, of which constituting amino acid residue numbers were three to six, by adopting an alternative molecular imprinting. It was made clear that the number four, in other words, the tetrapeptide derivative, is the best candidate material to form a chiral recognition site.
Keywords:chiral recognition  optical resolution  molecular recognition  molecular imprinting  oligopeptide
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