Kinetic studies on oxidation of aromatic donor molecules by horseradish peroxidase and lactoperoxidase |
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Authors: | Sandeep Modi Digamber V. Behere |
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Affiliation: | (1) Centre for Mechanisms of Human Toxicity, University of Leicester, Leicester, UK;(2) Chemical Physics Group TIFR, Bombay, India |
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Abstract: | Based on kinetic evidence, it has been shown for the first time that the mode of binding of aromatic donor molecules is similar in horseradish peroxidase and lactoperoxidase; also that the nature of the heme plays an important role in the reaction with hydrogen peroxide, and has no effect on the reaction of the intermediate compound II with aromatic substrates. |
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Keywords: | aromatic donor molecules horseradish peroxidase kinetics lactoperoxidase |
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