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| 壳聚糖及其衍生物抗肿瘤作用研究进展 | |
| 引用本文： | 张爱英,王学东,程远征,李明福.壳聚糖及其衍生物抗肿瘤作用研究进展[J].现代生物医学进展,2010,10(5). |
| 作者姓名： | 张爱英 王学东 程远征 李明福 |
| 作者单位： | 1. 潍坊医学院免疫学教研室山东省高校免疫学重点实验室,山东,潍坊,261053 2. 潍坊医学院化学教研室,山东,潍坊,261053 3. 潍坊医学院外科学教研室,山东,潍坊,261053 |
| 基金项目： | 山东省高等学校科技计划项目(J09LB57) |
| 摘 要： | 壳聚糖为天然多糖甲壳素脱除部分乙酰基的产物,是自然界存在的唯一碱性多糖,无毒,可生物降解,具有免疫功能和良好的生物相容性。近年发现,壳聚糖具有抗肿瘤作用,却因其难溶于水及中性溶剂而影响其应用,壳聚糖衍生物改善了壳聚糖的这个缺点,也具有更广泛的药理作用。本文对壳聚糖及其壳聚糖衍生物在抗肿瘤方面的研究情况做了综述。 |
| 关 键 词： | 壳聚糖 衍生物 抗肿瘤 |
The Research Advance on the antitumor effect of chitosan and its derivatives |
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| ZHANG Ai-ying WANG Xue-dong FENG Yuan-zheng.The Research Advance on the antitumor effect of chitosan and its derivatives[J].Progress in Modern Biomedicine,2010,10(5). | |
| Authors: | ZHANG Ai-ying WANG Xue-dong FENG Yuan-zheng |
| Institution: | ZHANG Ai-ying1 WANG Xue-dong2 FENG Yuan-zheng2 (1 Dept.of Immunology,Weifang medical University Shangdong Key Laboratory of Immunology,Weifang,China,261053,2 Dept.of Chemistry,Weifang Medical University,3 Dept.of Surgery,Weifang Medical University) |
| Abstract: | Chitosan,the part deacetylation product of chitin,is the only alkaline polysaccharides in the nature.It is innocuity,biodegradable,immunity and favorable biocompatible.The antitumor effect of chitosan is found in these years,but it can not be used widely because of the insoluble point.Chitosan derivatives have more comprehensive pharmacological action,improving the weak point of insoluble.The text reviews the antitumor research of chitosan and its derivatives. |
| Keywords: | Chitosan Derivatives Antitumor |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |