(1) Department of Heart-Lung Diseases, Lund University Hospital, Lund, Sweden;(2) Departments of Psychology, Lund University, Lund, Sweden;(3) Department of Medical Neurochemistry, Lund University Hospital, Lund, Sweden
Abstract:
Background
The brain-derived protein S100B has been shown to be a useful marker of brain injury of different etiologies. Cognitive dysfunction after cardiac surgery using cardiopulmonary bypass has been reported to occur in up to 70% of patients. In this study we tried to evaluate S100B as a marker for cognitive dysfunction after coronary bypass surgery with cardiopulmonary bypass in a model where the inflow of S100B from shed mediastinal blood was corrected for.
