Illuminating the molecular basis of gene-for-gene resistance; Arabidopsis thaliana RRS1-R and its interaction with Ralstonia solanacearum popP2 |
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Authors: | Lahaye Thomas |
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Institution: | Institute of Genetics, Martin-Luther-Universit?t Halle-Wittenberg, 06099 (Saale), Halle, Germany. lahaye@genetik.uni-halle.de |
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Abstract: | Elucidation of the molecular basis of gene-for-gene interactions between disease-resistance (R) genes and pathogen avirulence (avr) genes has been a Holy Grail of plant pathology for the past decade. Recent studies of the R-avr interaction between RRS1-R and popP2 by Laurent Deslandes et al. provide new insights and suggest a direct physical association of the encoded proteins in support of a simplistic receptor-ligand model. However, careful consideration of the experimental findings reveals that they could also be explained by molecular linker proteins that mediate formation of a PopP2 and RRS1-R uniting complex. |
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