Bis-thiourea Metal Complexes with Enhanced Antiphytoviral Activity |
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Authors: | K. A. Davarski G. Schuster G. N. Vassilev |
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Affiliation: | Department of Inorganie Chemistry, Higher Institute of Chemical Technology, 8010 Bourgas, Bulgaria;Department of Life Sciences, Karl Marx University, Talstr. 33, DDR 7010 Leipzig, German Democratic Republic;Institute of Plant Physiology, Bulgarian Academy of Sciences, Sofia, Bulgaria |
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Abstract: | The activity of bis-thiourea, diallyl-bis-thiourea and in part of diphenyl-bis-thiourea against potato virus X (PVX) can be augmented considerably by complexation of the mentioned compounds with Cu±±, Ni±±, and Co±±. Contrary to this, complexation with Fe±± and Cd±± does not augment or reduce the antiphytoviral activity. Most antiphytoviral active are the diallyl-bis-thiourea complexes with Cu±±, Ni±± and Co±±. The antiphytoviral activity of the Cu±± and Cd±± complexes with bisthiourea can be additionally augmented by combined treatment with small amounts of 2,4-dioxohexahydro-l,3,5-triazine (DHT). |
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