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Anti-Listeria activities of Galleria mellonella hemolymph proteins |
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| Authors: | Mukherjee Krishnendu Abu Mraheil Mobarak Silva Silke Müller Daniela Cemic Franz Hemberger Jürgen Hain Torsten Vilcinskas Andreas Chakraborty Trinad |
| Affiliation: | 1Institute of Phytopathology and Applied Zoology, Justus Liebig University, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany;2Institute of Medical Microbiology, Justus Liebig University, Frankfurter Strasse 107, 35392 Giessen, Germany;3 Institute for Biochemical Engineering and Analytics, University of Applied Sciences Giessen-Friedberg, Wiesenstasse 14, 35390 Giessen, Germany |
| Abstract: | We report the use of antimicrobial hemolymph proteins from the model host Galleria mellonella as an inhibitor for various Listeria strains, providing a novel source for antilisterial therapeutics. We also have shown that specific virulence-associated genes known to mediate antimicrobial resistance of Listeria in mammalian models indicated a similar function in Galleria. |
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