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Metabolism of vanillic acid by Micromycetes
Authors:P. Guiraud  R. Steiman  F. Seigle-Murandi  J. -L. Benoit-Guyod
Affiliation:(1) Laboratoire de Botanique, Cryptogamie, Biologie Cellulaire et Génétique, Groupe pour l'Etude du Devenir des Xénobiotiques dans l'Environnement (GEDEXE), UFR de Pharmacie, Université J. Fourier (Grenoble I), BP 138, 38243 Meylan Cédex, France;(2) Laboratoire de Toxicologie et Ecotoxicologie, GEDEXE, UFR de Pharmacie, Université J. Fourier (Grenoble I), BP 138, 38243 Meylan Cédex, France
Abstract:The ability of 953 strains of Micromycetes to grow with vanillic acid (0.5 g/l) was investigated. Toxicity assays were performed on malt extract/agar medium, while consumption was estimated by growing fungi on solid synthetic medium with vanillic acid as sole carbon source. More than half of the tested strains grew in both conditions. After cultivation on solid media, 296 strains were selected and cultivated in liquid synthetic medium. These experiments allowed division of the Micromycetes into different groups according to their consumption of the phenolic compound and the appearance of new metabolites. Results were related to the taxonomic position of the strains.
Keywords:Consumption  Micromycetes  screening  toxicity  vanillic acid
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