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Synthesis of amino acid conjugates of 1,1′-dimethylferrocene: New chiral conjugates
Authors:Demyan E Prokopchuk
Institution:Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Sask, Canada S7N 5C9
Abstract:Syntheses of diastereomeric mixtures of 1,1′-dimethylferrocene-2-Ala-OMe (3) and 1,1′-dimethylferrocene-3-Ala-OMe (4) are reported by peptide coupling of L-Ala-OMe to the enantiomeric mixtures of the corresponding acids, 1,1′-dimethylferrocene-2-carboxylic acid (1) and 1,1′-dimethylferrocene-3-carboxylic acid (2).
Keywords:Dimethylferrocene  Chirality  Regioisomers  Ferrocenoyl amino acids
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