Interactions of progesterone and dihydroprogesterone with dihydrotestosterone on estrogen activated sexual receptivity in female mice |
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Authors: | William G. Luttge Nicholas R. Hall |
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Affiliation: | Department of Neuroscience and Center for Neurobiological Sciences, University of Florida College of Medicine, Gainesville, Florida 32610 USA |
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Abstract: | Lordosis behavior in response to a mounting stimulation was quantified in ovariectomized female CD-1 and SW mice primed with estradiol benzoate and either progesterone or dihydroprogesterone. Both progestins were effective in stimulating receptivity, in CD-1 females, while only progesterone was effective in SW females. Dihydrotestosterone given concurrently with both the estrogen and progestin injections was found to have no effect on progesterone stimulated receptivity, but it produced a dose related inhibition of receptivity in the dihydroprogesterone treated females. |
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