Rabbit brown adipose tissue uncoupling protein MRNA: use of only one of two polyadenylation signals in its processing |
| |
| Authors: | A G Balogh R G Ridley H V Patel K B Freeman |
| |
| Institution: | Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada. |
| |
| Abstract: | A cDNA containing the complete coding sequence of rabbit brown adipose tissue uncoupling protein was isolated and sequenced. The coding region is 80.6% identical to rat UCP cDNA and the protein is about 86% identical to the rat and hamster proteins. Despite the presence of 2 AATAAA polyadenylation consensus sequences in rabbit UCP cDNA, only one rabbit UCP mRNA was detected indicating that only the 3'-downstream signal is used in contrast to rat and mouse where both are used. |
| |
| Keywords: | |
|
|
