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The effect of feeding on plasma immunoreactive ACTH and beta-endorphin levels in newborn infant.
Authors:M Gemelli  R Manganaro  F De Luca  C Imperatore  G Costa  C Mamì
Institution:Institute of Clinica Pediatrica, University of Messina, Italy.
Abstract:In order to clarify whether an interaction between endogenous opioids and feeding occurs at birth, we studied Beta-endorphin (beta-EP) and ACTH plasma levels in response to a feed of 10% glucose, or formula, in 120 healthy full-term infants. Neither postprandial beta-EP nor ACTH increases were found at the 24th hour or on the fourth day of life. beta-EP physiology in newborn infants seems to be different from adults.
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