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Cytogenetic mapping of five YAC clones to human chromosome region 2q31 --> q32.1 in relation to the FRA2G common fragile site
Authors:Pelliccia Franca  Limongi Maria Zaira  Gaddini Lucia  Russo Maria Teresa  Rocchi Angela
Affiliation:(1) Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, P.le Aldo Moro, 5, 00185 Roma, Italy
Abstract:In this work, five YAC clones have been mapped by fluorescent in situ hybridization (FISH) to human chromosome region 2q31 rarr q32.1 and ordered in relation to each other and to the FRA2G common fragile site. YAC clones that span the fragile site have been identified. Moreover a deleted HOXD 13 gene has been identified on the 942D2 YAC.
Keywords:FISH mapping  fragile site  HOXD13 gene  YAC clone
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