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Quantitative analysis of the ribbon synapse number of cochlear inner hair cells in C57BL/6J mice using the three-dimensional modeling method
Authors:Ke Liu  ShuNa Li  XueJun Jiang
Affiliation:Department of Otolaryngology, the First Affiliated Hospital, China Medical University, Shenyang 110001, China
Abstract:In mammals,the ribbon synapses of cochlear inner hair cells are a synaptic structure of the first sensory nerve in the pathway of acoustical signal transmission to the acoustic center,and it is directly involved in voice coding and neurotransmitter release. It is difficult to quantitatively analyze the ribbon synaptic number only using an electron microscope,because the ribbon synaptic number is relatively limited and their location is deep. In this study,the specific presynaptic structure-RIBEYE,and non-sp...
Keywords:inner hair cells  Ribbon synapses  laser scanning confocal microscope  three-dimensional modeling  
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