A mathematical model of the response of semicircular canal and otolith to head rotation under gravity |
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| Authors: | Alexandrov V V Alexandrova T B Astakhova T G Kulikovskaya N V Kurilov V I Migunov S S Shulenina N E Soto E Vega R |
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| Affiliation: | Faculty of Mechanics and Mathematics, Moscow State University, Russia. i_nelly@hotmail.com |
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| Abstract: | The mathematical model of the system composed of two sensors: semicircular canal and sacculus, is presented. The system is described by three series of blocks: biomechanical block, mechanoelectrical transduction mechanism and hair cell ionic currents and membrane potential dynamics. The response of the aforecited system to various stimuli (head rotation under gravity and falling) was investigated. The identification of the model parameters was fulfilled for the experimental data, obtained for the axolotle (Ambystoma tigrinum) in Institute of Physiology, Autonomous University of Puebla, Mexico. The comparative analysis of canal and sacculus membrane potential was realized. |
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