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An oral cancer biobank initiative: a platform for multidisciplinary research in a developing country |
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| Authors: | Rosnah Binti Zain Vimmitra Athirajan Wan Maria Nabillah Ghani Ishak Abdul Razak Raja Jalaludin Raja Latifah Siti Mazlipah Ismail Atiya Abdul Sallam Anita Zarina Bustam Zainal Ariff Abdul Rahman Adam Hussien Norain Talib Sok Ching Cheong Amin Jallaludin |
| Affiliation: | 1. Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University Malaya, 50603, Lembah Pantai, Kuala Lumpur, Malaysia 2. Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University Malaya, Kuala Lumpur, Malaysia 3. Department of Community Dentistry, Faculty of Dentistry, University Malaya, Kuala Lumpur, Malaysia 4. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University Malaya, Kuala Lumpur, Malaysia 5. Dean’s Office, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia 6. Department of Restorative Dentistry, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia 7. Oral Health Division, Ministry of Health, Putrajaya, Malaysia 8. Oral Cancer Research Team, Cancer Research Initiatives Foundation, Kuala Lumpur, Malaysia 9. Department of Otorhinolaringology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia |
| Abstract: | Identification of diagnostic markers for early detection and development of novel and therapeutic agents for effective patient management are the main motivation for cancer research. Biological specimens from large cohort and case-control studies which are crucial in providing successful research outcomes are often the limiting factor that hinders research efforts, especially in developing countries. Therefore, the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS) were established to systematically collect large number of samples with comprehensive sociodemographic, clinicopathological, management strategies, quality of life and associated patient follow-up data to facilitate oral cancer research in Malaysia. The MOCDTBS also promotes sharing among researchers and the development of a multidisciplinary research team. The following article aims to describe the process of setting-up and managing the MOCDTBS. |
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