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Saccharomyces cerevisiae alpha-factor prevents formation of glycoproteins in a cells |
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| Authors: | P Orlean G Seebacher W Tanner |
| Institution: | Biochemisches Institut der Universität Zürich, Zürichbergstrasse 4, CH-8028 Zürich, Switzerland |
| Abstract: | alpha-Factor inhibits incorporation of 14C]glucosamine into water-soluble and into SDS-extractable glycoproteins to about 90%. The incorporation into chitin is not affected and the same is true for 14C]phenylalanine incorporation into protein. The inhibition of glycoprotein synthesis is specific for a cells. |
| Keywords: | Protein secondary structure prediction Model building Protein design Synthetic DDT-binding polypeptide Crystallization of artificial polypeptide DDT |
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