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Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy
Institution:1. Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States;2. Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States;3. Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and Weill Cornell Medical College, New York, NY, United States;4. Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States;1. Department of Cardiovascular Medicine, University of Münster, Münster, Germany;2. Institute for Molecular Cell Biology, University of Münster, Münster, Germany;3. Cells-in-Motion Cluster of Excellence, EXC 1003– CiM, University of Münster, Münster, Germany
Abstract:
Keywords:NOD-like receptors  Hyperglycemia  Oxidative stress  mRNA stability  Gene therapy  Free radicals
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