Neisseria meningitidis: heterogenicity in the outer membrane proteins released into the growth medium |
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Authors: | E Jascolt S Siddiqui G R Chaudhry A R Bhatti |
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Affiliation: | Biomedical Defence Section, Defence Research Establishment Suffield, Ralston, Alberta, Canada. |
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Abstract: | Eight strains of Neisseria meningitidis belonging to different serogroups were analysed for their virulence in mice and their release of outer membrane proteins into the medium during growth. All strains released proteins. No detectable lipopolysaccharide was observed. However, SDS-PAGE showed a heterogenicity in the protein number and profile among the different strains of N. meningitidis tested. |
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