牛胰多肽对大鼠胰腺外分泌细胞膜流动性的影响 |
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引用本文: | 顾增发,王志均,聂松青,林克椿. 牛胰多肽对大鼠胰腺外分泌细胞膜流动性的影响[J]. 生物物理学报, 1988, 4(3): 179-183 |
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作者姓名: | 顾增发 王志均 聂松青 林克椿 |
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作者单位: | 北京医科大学消化生殖生理教研室(顾增发,王志均),北京医科大学生物物理教研室(聂松青),北京医科大学生物物理教研室(林克椿) |
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摘 要: | 胰多肽为含有36个氨基酸残基的直链多肽,是70年代后期发现的一种胃肠激素.本工作用荧光偏振法观察到,牛磺胆酸钠降低胰腺外分泌细胞膜的平均微粘度,而牛胰多肽能抑制牛磺胆酸钠的这一作用.结果提示,牛胰多肽有稳定胰腺外分泌细胞膜流动性的功能.
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EFFECTS OF BOVINE PANCREATIC POLYPEPTIDE ON MEMBRANE FLUIDITY OF PANCREATIC EXOCRINE CELLS IN THE RAT |
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Abstract: | Pancreatic polypeptide is a straight chain polypeptide with 36-amino acid residues and a younger gut hormone.By fluorescence polarization method,it is observed in this paper that sodium taurocholate lowers membrane microviscosity of pancreatic exocrine cells.However,this action of sodium taurocholate is inhibited by BPP.The results suggest that BPP may have a function to stabilize membrane fluidity of pancreatic exocrine cells. |
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