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Copy-number variation introduced by long transgenes compromises mouse male fertility independently of pachytene checkpoints
Authors:Mihola  Ondrej  Kobets  Tatyana  Krivankova  Klara  Linhartova  Eliska  Gasic  Srdjan  Schimenti  John C.  Trachtulec  Zdenek
Abstract:Chromosoma - Long transgenes are often used in mammalian genetics, e.g., to rescue mutations in large genes. In the course of experiments addressing the genetic basis of hybrid sterility caused by...
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