Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries. |
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| Authors: | S Kornbluth K E Paulson and H Hanafusa |
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| Institution: | Rockefeller University, New York, New York 10021-6399. |
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| Abstract: | In an attempt to clone protein tyrosine kinases, antiphosphotyrosine antibodies were used to screen lambda gt11 cDNA expression libraries. By this method, a 2.5-kilobase cDNA encoding a novel tyrosine kinase was isolated from a mouse liver cDNA library. This new gene is most closely related to the receptor tyrosine kinases ret, fms, and kit. |
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