Immune-modulating activities of polysaccharides extracted from brown algae Hizikia fusiforme |
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Authors: | Sang Chul Jeong Yong Tae Jeong Sang Myung Lee |
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Affiliation: | 1. HK Bio, Business Incubator, Daegu Haany University, Gyeongsan, Republic Korea;2. Korea Ginseng Corporation Central Research Institute, Daejeon, Republic of Korea |
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Abstract: | The immuno-modulating activities of seaweed (Hizikia fusiforme) extracts on murine macrophage and splenocyte were studied in vitro. Polysaccharide (HFP) exhibited the potential macrophage stimulating effects than water extract (HFW) such as NO production and enhanced pro-inflammatory cytokines on the Raw 264.7 cells and splenocytes. From the mono-sugar composition, HFP-associated fucose based on HFP of H. fusiforme acts as immune modulator. |
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Keywords: | Hizikia fusiforme splenocyte macrophage polysaccharide cytokines |
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