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Immune-modulating activities of polysaccharides extracted from brown algae Hizikia fusiforme
Authors:Sang Chul Jeong  Yong Tae Jeong  Sang Myung Lee
Affiliation:1. HK Bio, Business Incubator, Daegu Haany University, Gyeongsan, Republic Korea;2. Korea Ginseng Corporation Central Research Institute, Daejeon, Republic of Korea
Abstract:The immuno-modulating activities of seaweed (Hizikia fusiforme) extracts on murine macrophage and splenocyte were studied in vitro. Polysaccharide (HFP) exhibited the potential macrophage stimulating effects than water extract (HFW) such as NO production and enhanced pro-inflammatory cytokines on the Raw 264.7 cells and splenocytes. From the mono-sugar composition, HFP-associated fucose based on HFP of H. fusiforme acts as immune modulator.
Keywords:Hizikia fusiforme  splenocyte  macrophage  polysaccharide  cytokines
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